DIABETES INSIPIDUS IN A PATIENT WITH BRONCHOGENIC CARCINOMA AND SECONDARIES TO THE HYPOTHALAMUS - CASE REPORT
*DIALLO M, FAYE M1, SY EHC1, AL FALASI M1, BERHOUMA M, PERRIN G
Department of Neurosurgery, Neurological & Neurosurgical Hospital Pierre WERTHEIMER, Lyon, France.
E-mail: mdiallo5@gmail.com
1Department of Neurosurgery, Hopital Nord Marseille, Marseille, France.
*Correspondence
Grant support: None
Conflict of interest: None
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ABSTRACT
Background:We present a middle-aged man with features of diabetes insipidus, visual and mental impairments as a result of metastases from bronchogenic carcinoma. This case is being presented because it is uncommon; high index of suspicion and the relevant imaging techniques are required for diagnosis. Surgical resection of the pituitary secondaries with post-operative chemo-radiation brought resolution of symptoms.
In conclusion, hypothalamic metastases are uncommon and are often associated with compression of the pituitary gland and optic chiasma leading to diabetes insipidus, visual impairment and mental defects. MRI for diagnosis and surgical resection followed with chemoradiation lead to improvement of symptoms but mortality is high.
Key words: Bronchogenic carcinoma, Hypothalamic secondaries, Diabetes insipidus.
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